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Olig2 Targets Chromatin Remodelers To Enhancers To Initiate Oligodendrocyte Differentiation
Establishment of oligodendrocyte identity is crucial for subsequent events of myelination in the central nervous system (CNS). Here, we demonstrate that activation of ATP-dependent SWI/SNF chromatin-remodeling enzyme Smarca4/Brg1 at the differentiation onset is necessary and sufficient to initiate a...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553550/ https://ncbi.nlm.nih.gov/pubmed/23332759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.006 |
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