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Molecular regulation of CRAC channels and their role in lymphocyte function
Calcium (Ca(2+)) influx is required for the activation and function of all cells in the immune system. It is mediated mainly by store-operated Ca(2+) entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels located in the plasma membrane. CRAC channels are composed of ORAI proteins that...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553310/ https://ncbi.nlm.nih.gov/pubmed/23052215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1175-2 |
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