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A secreted decoy of InR antagonizes insulin/IGF signaling to restrict body growth in Drosophila

Members of the insulin peptide family have conserved roles in the regulation of growth and metabolism in a wide variety of metazoans. Drosophila insulin-like peptides (Dilps) promote tissue growth through the single insulin-like receptor (InR). Despite the important role of Dilps in nutrient-depende...

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Detalhes bibliográficos
Main Authors: Okamoto, Naoki, Nakamori, Rinna, Murai, Tomoka, Yamauchi, Yuki, Masuda, Aya, Nishimura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553286/
https://ncbi.nlm.nih.gov/pubmed/23307869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.204479.112
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