MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma

BACKGROUND: MicroRNAs are short regulatory RNAs that negatively modulate protein expression at a post-transcriptional and/or translational level and are deeply involved in the pathogenesis of several types of cancers. Specifically, microRNA-221 (miR-221) is overexpressed in many human cancers, where...

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Detalhes bibliográficos
Main Authors: Zhao, Guangyi, Cai, Chengkui, Yang, Tongtao, Qiu, Xiuchun, Liao, Bo, Li, Wei, Ji, Zhenwei, Zhao, Jian, Zhao, Haien, Guo, Mingjun, Ma, Qiong, Xiao, Chun, Fan, Qingyu, Ma, Baoan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553141/
https://ncbi.nlm.nih.gov/pubmed/23372675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053906
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