Graphical Modeling of Gene Expression in Monocytes Suggests Molecular Mechanisms Explaining Increased Atherosclerosis in Smokers

Smoking is a risk factor for atherosclerosis with reported widespread effects on gene expression in circulating blood cells. We hypothesized that a molecular signature mediating the relation between smoking and atherosclerosis may be found in the transcriptome of circulating monocytes. Genome-wide e...

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Détails bibliographiques
Auteurs principaux: Verdugo, Ricardo A., Zeller, Tanja, Rotival, Maxime, Wild, Philipp S., Münzel, Thomas, Lackner, Karl J., Weidmann, Henri, Ninio, Ewa, Trégouët, David-Alexandre, Cambien, François, Blankenberg, Stefan, Tiret, Laurence
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553098/
https://ncbi.nlm.nih.gov/pubmed/23372645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050888
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