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Imaging CXCL12-CXCR4 Signaling in Ovarian Cancer Therapy

Chemokine CXCL12 and receptor CXCR4 have emerged as promising therapeutic targets for ovarian cancer, a disease that continues to have a dismal prognosis. CXCL12-CXCR4 signaling drives proliferation, survival, and invasion of ovarian cancer cells, leading to tumor growth and metastasis. Pleiotropic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Salomonnson, Emma, Stacer, Amanda C., Ehrlich, Anna, Luker, Kathryn E., Luker, Gary D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553093/
https://ncbi.nlm.nih.gov/pubmed/23372646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051500
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