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Imaging CXCL12-CXCR4 Signaling in Ovarian Cancer Therapy
Chemokine CXCL12 and receptor CXCR4 have emerged as promising therapeutic targets for ovarian cancer, a disease that continues to have a dismal prognosis. CXCL12-CXCR4 signaling drives proliferation, survival, and invasion of ovarian cancer cells, leading to tumor growth and metastasis. Pleiotropic...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553093/ https://ncbi.nlm.nih.gov/pubmed/23372646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051500 |
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