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Overexpression of Wild-Type but Not C134W Mutant FOXL2 Enhances GnRH-Induced Cell Apoptosis by Increasing GnRH Receptor Expression in Human Granulosa Cell Tumors

The etiology of granulosa cell tumors (GCTs) is largely unknown. The primary mode of treatment is surgical, however not all women are cured by surgery alone. Thus, it is important to develop improved treatments through a greater understanding of the molecular mechanisms that contribute to this disea...

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Detalhes bibliográficos
Main Authors: Cheng, Jung-Chien, Klausen, Christian, Leung, Peter C. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553060/
https://ncbi.nlm.nih.gov/pubmed/23372819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055099
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