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The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers
SWI/SNF is a multi-subunit chromatin remodeling complex that uses the energy of ATP hydrolysis to reposition nucleosomes, thereby modulating gene expression. Accumulating evidence suggests that SWI/SNF functions as a tumor suppressor in some cancers. However, the spectrum of SWI/SNF mutations across...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552954/ https://ncbi.nlm.nih.gov/pubmed/23355908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055119 |
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