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Clinical development of phosphatidylinositol 3-kinase inhibitors for cancer treatment

The phosphatidylinositol 3-kinase (PI3K) pathway is commonly deregulated in cancer. In recent years, the results of the first phase I clinical trials with PI3K inhibitors have become available. In comparison to other targeted agents such v-raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibito...

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Detalhes bibliográficos
Main Authors: Brana, Irene, Siu, Lillian L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552942/
https://ncbi.nlm.nih.gov/pubmed/23232172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-10-161
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