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Atg1 kinase regulates early and late steps during autophagy
The notion that phosphorylation constitutes a major mechanism to induce autophagy was established 15 years ago when a conserved Atg1/ULK kinase family was identified as an essential component of the autophagy machinery. The key observation was that starved atg1Δ cells lack autophagosomes in the cyto...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552892/ https://ncbi.nlm.nih.gov/pubmed/23108207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22584 |
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