Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

Autophagy is an intracellular trafficking pathway sequestering cytoplasm and delivering excess and damaged cargo to the vacuole for degradation. The Atg1/ULK1 kinase is an essential component of the core autophagy machinery possibly activated by binding to Atg13 upon starvation. Indeed, we found tha...

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Detalhes bibliográficos
Main Authors: Kraft, Claudine, Kijanska, Monika, Kalie, Eyal, Siergiejuk, Edyta, Lee, Sung Sik, Semplicio, Giuseppe, Stoffel, Ingrid, Brezovich, Andrea, Verma, Mayanka, Hansmann, Isabella, Ammerer, Gustav, Hofmann, Kay, Tooze, Sharon, Peter, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442273/
https://ncbi.nlm.nih.gov/pubmed/22885598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.225
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