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Porous silicon-based nanostructured microparticles as degradable supports for solid-phase synthesis and release of oligonucleotides

We describe the preparation of several types of porous silicon (pSi) microparticles as supports for the solid-phase synthesis of oligonucleotides. The first of these supports facilitates oligonucleotide release from the nanostructured support during the oligonucleotide deprotection step, while the s...

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Detalhes bibliográficos
Main Authors: McInnes, Steven J P, Voelcker, Nicolas H
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552826/
https://ncbi.nlm.nih.gov/pubmed/22784812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1556-276X-7-385
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