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Autophagy inhibition plays the synergetic killing roles with radiation in the multi-drug resistant SKVCR ovarian cancer cells

PURPOSE: Autophagy has attracted attentions as a novel mechanism for tumor development. In this study Human ovarian carcinoma cell line SKOV3 and multidrug-resistant phenotype SKVCR cells were used and the roles of autophagy in radiation-induced cell death were analyzed. METHODS AND MATERIALS: Cell...

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Main Authors: Liang, Bing, Kong, Dejuan, Liu, Yang, Liang, Nan, He, Mengzi, Ma, Shumei, Liu, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552756/
https://ncbi.nlm.nih.gov/pubmed/23244773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-7-213
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