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The Tumor Suppressor, p53, Contributes to Radiosensitivity of Lung Cancer Cells by Regulating Autophagy and Apoptosis

PURPOSE: Cell death is one of the most important endpoints of radiosensitivity. The tumor suppressor p53 participates not only in regulation of apoptosis, but also in autophagy mechanism. In this study, H1299-P53 (with wild-type p53) and H1299-175H (with mutant 175H) were used, and the effects of p5...

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Detalhes bibliográficos
Main Authors: Cheng, Guanghui, Kong, Dejuan, Hou, Xue, Liang, Bing, He, Mengzi, Liang, Nan, Ma, Shumei, Liu, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589888/
https://ncbi.nlm.nih.gov/pubmed/23268708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2012.1297
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