Integrated lipidomics and transcriptomic analysis of peripheral blood reveals significantly enriched pathways in type 2 diabetes mellitus

BACKGROUND: Insulin resistance is a key element in the pathogenesis of type 2 diabetes mellitus. Plasma free fatty acids were assumed to mediate the insulin resistance, while the relationship between lipid and glucose disposal remains to be demonstrated across liver, skeletal muscle and blood. METHO...

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Autori principali: Zhao, Chen, Mao, Jinghe, Ai, Junmei, Shenwu, Ming, Shi, Tieliu, Zhang, Daqing, Wang, Xiaonan, Wang, Yunliang, Deng, Youping
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552685/
https://ncbi.nlm.nih.gov/pubmed/23369247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-S1-S12
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