Integrated lipidomics and transcriptomic analysis of peripheral blood reveals significantly enriched pathways in type 2 diabetes mellitus

BACKGROUND: Insulin resistance is a key element in the pathogenesis of type 2 diabetes mellitus. Plasma free fatty acids were assumed to mediate the insulin resistance, while the relationship between lipid and glucose disposal remains to be demonstrated across liver, skeletal muscle and blood. METHO...

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Main Authors: Zhao, Chen, Mao, Jinghe, Ai, Junmei, Shenwu, Ming, Shi, Tieliu, Zhang, Daqing, Wang, Xiaonan, Wang, Yunliang, Deng, Youping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552685/
https://ncbi.nlm.nih.gov/pubmed/23369247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-S1-S12
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