Increased Frequency of Suppressive Regulatory T Cells and T-cell Mediated Antigen Loss Results in Murine Melanoma Recurrence

Therapeutic treatment of large established tumors using immunotherapy has yielded few promising results. We investigated if adoptive transfer of tumor-specific CD8(+) T cells together with tumor-specific CD4(+) T cells would mediate regression of large established B16BL6-D5 (D5) melanomas in lymphop...

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Main Authors: Jensen, Shawn M., Twitty, Christopher G., Maston, Levi D., Antony, Paul A., Lim, May, Hu, Hong-Ming, Petrausch, Ulf, Restifo, Nicholas P., Fox, Bernard A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552612/
https://ncbi.nlm.nih.gov/pubmed/22723522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103822
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