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The cargo of CRPPR-conjugated liposomes crosses the intact murine cardiac endothelium

Ligand-conjugated liposomes and other nano-sized constructs are attractive drug carriers due to their extended plasma circulation; however, limited data are available as to whether their cargo can traverse the endothelium of solid organs. To determine whether the cargo of endothelially-targeted lipo...

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Detalhes bibliográficos
Main Authors: Zhang, Hua, Li, Ning, Sirish, Padmini, Mahakian, Lisa, Ingham, Elizabeth, Curry, Fitz-Roy, Yamada, Soichiro, Chiamvimonvat, Nipavan, Ferrara, Katherine W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552610/
https://ncbi.nlm.nih.gov/pubmed/22776291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.06.038
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