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Differential activation of human T cells to allogeneic endothelial cells, epithelial cells and fibroblasts in vitro

BACKGROUND: In the direct pathway, T cells recognize intact donor major histocompatability complexes and allogeneic peptide on the surface of donor antigen presenting cells (APCs). Indirect allorecognition results from the recognition of processed alloantigen by self MHC complexes on self APCs. In t...

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Main Authors: Samsonov, Dmitry, Geehan, Christopher, Woda, Craig B, Briscoe, David M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552572/
https://ncbi.nlm.nih.gov/pubmed/23369287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-1440-1-4
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