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High-Resolution Differential Ion Mobility Spectrometry of a Protein

Use of elevated electric fields and helium-rich gases has recently enabled differential IMS with resolving power up to R ~ 300. Here we applied that technique to a protein (namely, ubiquitin), achieving R up to ~80 and separating many previously unresolved conformers. While still limited by conforma...

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Bibliografiske detaljer
Main Authors: Shvartsburg, Alexandre A., Smith, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552553/
https://ncbi.nlm.nih.gov/pubmed/23244633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3029129
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