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Separation of Peptide Isomers with Variant Modified Sites by High-Resolution Differential Ion Mobility Spectrometry

Many proteins and proteolytic peptides incorporate the same post-translational modification (PTM) at different sites, creating multiple localization variants with different functions or activities that may coexist in cells. Current analytical methods based on liquid chromatography (LC) followed by t...

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Detalhes bibliográficos
Main Authors: Shvartsburg, Alexandre A., Creese, Andrew J., Smith, Richard D., Cooper, Helen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973842/
https://ncbi.nlm.nih.gov/pubmed/20843012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac101878a
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