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Separation of a Set of Peptide Sequence Isomers Using Differential Ion Mobility Spectrometry
Protein identification in bottom-up proteomics requires disentangling isomers of proteolytic peptides, a major class of which are sequence inversions. Their separation using ion mobility spectrometry (IMS) has been limited to isomeric pairs. Here we demonstrate baseline separation of all seven 8-mer...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173593/ https://ncbi.nlm.nih.gov/pubmed/21863819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201640d |
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