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Separation of a Set of Peptide Sequence Isomers Using Differential Ion Mobility Spectrometry

Protein identification in bottom-up proteomics requires disentangling isomers of proteolytic peptides, a major class of which are sequence inversions. Their separation using ion mobility spectrometry (IMS) has been limited to isomeric pairs. Here we demonstrate baseline separation of all seven 8-mer...

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Detaylı Bibliyografya
Asıl Yazarlar: Shvartsburg, Alexandre A., Creese, Andrew J., Smith, Richard D., Cooper, Helen J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173593/
https://ncbi.nlm.nih.gov/pubmed/21863819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201640d
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