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Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

Adoptive transfer of thymus-derived natural regulatory T-cells (nTregs) effectively suppresses disease in murine models of autoimmunity and graft-versus-host disease (GVHD). TGFβ induces Foxp3 expression and suppressive function in stimulated murine CD4+25- T cells, and these induced Treg (iTregs),...

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Detalhes bibliográficos
Main Authors:	Hippen, K.L., Merkel, S.C., Schirm, D.K., Nelson, C., Tennis, N.C., Riley, J.L., June, C.H., Miller, J.S., Wagner, J.E., Blazar, B.R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	2011
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3552455/ https://ncbi.nlm.nih.gov/pubmed/21564534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03558.x
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Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

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