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Fusion-pore expansion during syncytium formation is restricted by an actin network

Cell-cell fusion in animal development and in pathophysiology involves expansion of nascent fusion pores formed by protein fusogens to yield an open lumen of cell-size diameter. Here we explored the enlargement of micron-scale pores in syncytium formation, which was initiated by a well-characterized...

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Bibliographic Details
Main Authors: Chen, Andrew, Leikina, Eugenia, Melikov, Kamran, Podbilewicz, Benjamin, Kozlov, Michael M., Chernomordik, Leonid V.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552434/
https://ncbi.nlm.nih.gov/pubmed/18946025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.032169
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