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Catalytic Enantioselective Cyclization and C3-Fluorination of Polyenes

(xylyl-phanephos)Pt(2+) in combination with XeF(2) mediates the consecutive diastereoselective cation-olefin cyclization/fluorination of polyene substrates. Isolated yields were typically in the 60s while enantioselectivies reached as high as 87%. The data are consistent with a stereoretentive fluor...

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Détails bibliographiques
Auteurs principaux: Cochrane, Nikki A., Nguyen, Ha, Gagne, Michel R.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552331/
https://ncbi.nlm.nih.gov/pubmed/23282101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3116795
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