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Mechanisms for Ribotoxin-induced Ribosomal RNA Cleavage

The Type B trichothecene deoxynivalenol (DON), a ribotoxic mycotoxin known to contaminate cereal-based foods, induces ribosomal RNA (rRNA) cleavage in the macrophage via p38-directed activation of caspases. Here we employed the RAW 264.7 murine macrophage model to test the hypothesis that this rRNA...

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Bibliografske podrobnosti
Main Authors: He, Kaiyu, Zhou, Hui-Ren, Pestka, James J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552329/
https://ncbi.nlm.nih.gov/pubmed/23022514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.09.017
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