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Dissection of the high rate constant for the binding of a ribotoxin to the ribosome
Restrictocin belongs to a family of site-specific ribonucleases that kill cells by inactivating the ribosome. The restrictocin–ribosome binding rate constant was observed to exceed 10(10) M(−1) s(−1). We have developed a transient-complex theory to model the binding rates of protein–protein and prot...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678469/ https://ncbi.nlm.nih.gov/pubmed/19346475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900291106 |
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