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Understanding the Role of Amphipathic Helices in N-BAR Domain Driven Membrane Remodeling

Endophilin N-BAR (N-terminal helix and Bin/amphiphysin/Rvs) domain tubulates and vesiculates lipid membranes in vitro via its crescent-shaped dimer and four amphipathic helices that penetrate into membranes as wedges. Like F-BAR domains, endophilin N-BAR also forms a scaffold on membrane tubes. Unli...

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Detalhes bibliográficos
Main Authors: Cui, Haosheng, Mim, Carsten, Vázquez, Francisco X., Lyman, Edward, Unger, Vinzenz M., Voth, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552260/
https://ncbi.nlm.nih.gov/pubmed/23442862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.006
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