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Structural Basis of Membrane Bending by the N-BAR Protein Endophilin

Functioning as key players in cellular regulation of membrane curvature, BAR-domain proteins bend bilayers and recruit interaction partners through poorly understood mechanisms. Using electron cryomicroscopy, we present reconstructions of full-length endophilin and its N-terminal N-BAR domain in the...

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Detalhes bibliográficos
Main Authors: Mim, Carsten, Cui, Haosheng, Gawronski-Salerno, Joseph A., Frost, Adam, Lyman, Edward, Voth, Gregory A., Unger, Vinzenz M
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319357/
https://ncbi.nlm.nih.gov/pubmed/22464326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.048
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