Control of hypercholesterolemia and atherosclerosis using the cholesterol recognition/interaction amino acid sequence of the translocator protein TSPO

The translocator protein (18-kDa) TSPO is an ubiquitous high affinity cholesterol-binding protein reported to be present in the endothelial and smooth muscle cells of the blood vessels; its expression dramatically increased in macrophages found in atherosclerotic plaques. A domain in the carboxy-ter...

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Main Authors: Lecanu, Laurent, Yao, Zhi-Xing, McCourty, Althea, Sidahmed, El-Khansa, Orellana, Maria E., Burnier, Miguel N., Papadopoulos, Vassilios
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552137/
https://ncbi.nlm.nih.gov/pubmed/23182766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2012.10.018
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