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Novel Androstenetriol Interacts with the Mitochondrial Translocator Protein and Controls Steroidogenesis

Steroid hormones are metabolically derived from multiple enzymatic transformations of cholesterol. The controlling step in steroid hormone biogenesis is the delivery of cholesterol from intracellular stores to the cytochrome P450 enzyme CYP11A1 in the mitochondrial matrix. The 18-kDa translocator pr...

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Bibliografiske detaljer
Main Authors: Midzak, Andrew, Akula, Nagaraju, Lecanu, Laurent, Papadopoulos, Vassilios
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058962/
https://ncbi.nlm.nih.gov/pubmed/21209087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203216
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