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Focal Adhesion Kinase Regulates the Localization and Retention of Pro-B Cells in Bone Marrow Microenvironments

Progenitor B cells reside in complex bone marrow microenvironments where they receive signals for growth and maturation. We reported previously that the CXCL12-FAK-VLA4 pathway plays an important role in progenitor B cell adhesion and migration. Here we have conditionally targeted in B cells Focal A...

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Detalhes bibliográficos
Main Authors: Park, Shin-Young, Wolfram, Peter, Canty, Kimberly, Harley, Brendan, Nombela-Arrieta, César, Pivarnik, Gregory, Manis, John, Beggs, Hilary E, Silberstein, Leslie E
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552136/
https://ncbi.nlm.nih.gov/pubmed/23264658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202639
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