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The environment and the origins of islet autoimmunity and Type 1 diabetes

Type 1 diabetes involves the specific destruction of the pancreatic islet β-cells, eventually resulting in a complete dependency of exogenous insulin. The clinical onset of diabetes is preceded by the appearance of autoantibodies against β-cell antigens. The human leukocyte antigen (HLA) region is t...

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Bibliographic Details
Main Authors: Regnéll, S. Eringsmark, Lernmark, Å.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552102/
https://ncbi.nlm.nih.gov/pubmed/23252770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dme.12099
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