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The environment and the origins of islet autoimmunity and Type 1 diabetes
Type 1 diabetes involves the specific destruction of the pancreatic islet β-cells, eventually resulting in a complete dependency of exogenous insulin. The clinical onset of diabetes is preceded by the appearance of autoantibodies against β-cell antigens. The human leukocyte antigen (HLA) region is t...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552102/ https://ncbi.nlm.nih.gov/pubmed/23252770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dme.12099 |
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