A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA

HIV-1 reverse transcription is achieved in the newly infected cell before viral DNA (vDNA) nuclear import. Reverse transcriptase (RT) has previously been shown to function as a molecular motor, dismantling the nucleocapsid complex that binds the viral genome as soon as plus-strand DNA synthesis init...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lyonnais, Sébastien, Gorelick, Robert J., Heniche-Boukhalfa, Fatima, Bouaziz, Serge, Parissi, Vincent, Mouscadet, Jean-François, Restle, Tobias, Gatell, Jose Maria, Le Cam, Eric, Mirambeau, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552025/
https://ncbi.nlm.nih.gov/pubmed/23017337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2012.09.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados