Sod1 Deficiency Reduces Incubation Time in Mouse Models of Prion Disease

Prion infections, causing neurodegenerative conditions such as Creutzfeldt-Jakob disease and kuru in humans, scrapie in sheep and BSE in cattle are characterised by prolonged and variable incubation periods that are faithfully reproduced in mouse models. Incubation time is partly determined by genet...

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Bibliographic Details
Main Authors: Akhtar, Shaheen, Grizenkova, Julia, Wenborn, Adam, Hummerich, Holger, Fernandez de Marco, Mar, Brandner, Sebastian, Collinge, John, Lloyd, Sarah E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551847/
https://ncbi.nlm.nih.gov/pubmed/23349894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054454
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