Comparison of Design Strategies for Promotion of β-Peptide 14-Helix Stability in Water

Many short β-peptides adopt well-defined conformations in organic solvents, but specialized stabilizing elements are required for folding to occur in aqueous solution. Several different strategies have been developed to stabilize the 14-helical secondary structure in water, and here we provide a dir...

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Bibliographic Details
Main Authors: Vaz, Esther, Pomerantz, William C., Geyer, Matthias, Gellman, Samuel H., Brunsveld, Luc
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551619/
https://ncbi.nlm.nih.gov/pubmed/18756554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800355
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