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Targeting Breast Carcinoma with Radioiodinated Anti-HER2 Nanobody

INTRODUCTION: With a molecular weight an order of magnitude lower than antibodies but possessing comparable affinities, Nanobodies (Nbs) are attractive as targeting agents for cancer diagnosis and therapy. An anti-HER2 Nb could be utilized to determine HER2 status in breast cancer patients prior to...

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Bibliographic Details
Main Authors: Pruszynski, Marek, Koumarianou, Eftychia, Vaidyanathan, Ganesan, Revets, Hilde, Devoogdt, Nick, Lahoutte, Tony, Zalutsky, Michael R.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551612/
https://ncbi.nlm.nih.gov/pubmed/23159171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.08.008
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