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Detection of Mutations in EGFR in Circulating Lung-Cancer Cells

BACKGROUND: The use of tyrosine kinase inhibitors to target the epidermal growth factor receptor gene (EGFR) in patients with non–small-cell lung cancer is effective but limited by the emergence of drug-resistance mutations. Molecular characterization of circulating tumor cells may provide a strateg...

詳細記述

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書誌詳細
主要な著者: Maheswaran, Shyamala, Sequist, Lecia V., Nagrath, Sunitha, Ulkus, Lindsey, Brannigan, Brian, Collura, Chey V., Inserra, Elizabeth, Diederichs, Sven, Iafrate, A. John, Bell, Daphne W., Digumarthy, Subba, Muzikansky, Alona, Irimia, Daniel, Settleman, Jeffrey, Tompkins, Ronald G., Lynch, Thomas J., Toner, Mehmet, Haber, Daniel A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551471/
https://ncbi.nlm.nih.gov/pubmed/18596266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0800668
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