In Vitro Exposure of Precision-Cut Lung Slices to 2-(4-Amino-3-Methylphenyl)-5-Fluorobenzothiazole Lysylamide Dihydrochloride (NSC 710305, Phortress) Increases Inflammatory Cytokine Content and Tissue Damage

The anticancer drug (2-[4-amino-3-methylphenyl]-5-fluorobenzothiazole lysylamide dihydrochloride) (NSC 710305, Phortress) is a metabolically activated prodrug that causes DNA adduct formation and subsequent toxicity. Preclinically, it was found that hepatic, bone marrow, and pulmonary toxicity prese...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Behrsing, Holger P., Furniss, Michael J., Davis, Myrtle, Tomaszewski, Joseph E., Parchment, Ralph E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551430/
https://ncbi.nlm.nih.gov/pubmed/23143926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs319
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