Ketamine-Induced Neuronal Damage and Altered N-Methyl-d-Aspartate Receptor Function in Rat Primary Forebrain Culture

Ketamine, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, is frequently used in pediatric general anesthesia. Accumulating evidence from animal experiments has demonstrated that ketamine causes neuronal cell death during the brain growth spurt. To elucidate the underlying mechanism...

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Bibliografiske detaljer
Main Authors: Liu, Fang, Patterson, Tucker A., Sadovova, Natalya, Zhang, Xuan, Liu, Shuliang, Zou, Xiaoju, Hanig, Joseph P., Paule, Merle G., Slikker, William, Wang, Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551423/
https://ncbi.nlm.nih.gov/pubmed/23065140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs296
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