Ketamine-Induced Neuronal Damage and Altered N-Methyl-d-Aspartate Receptor Function in Rat Primary Forebrain Culture

Ketamine, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, is frequently used in pediatric general anesthesia. Accumulating evidence from animal experiments has demonstrated that ketamine causes neuronal cell death during the brain growth spurt. To elucidate the underlying mechanism...

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Detalhes bibliográficos
Main Authors: Liu, Fang, Patterson, Tucker A., Sadovova, Natalya, Zhang, Xuan, Liu, Shuliang, Zou, Xiaoju, Hanig, Joseph P., Paule, Merle G., Slikker, William, Wang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551423/
https://ncbi.nlm.nih.gov/pubmed/23065140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs296
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