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RAS-Mediated Adaptive Mechanisms in Cardiovascular Tissues: Confounding Factors of RAS Blockade Therapy and Alternative Approaches

Since the classic experiments by Tigerstedt and Bergman that established the role of renin in hypertension a century ago, aggressive efforts have been launched to effectively block the renin-angiotensin system (RAS). Blockade of RAS is advocated at multiple levels by direct renin inhibitor, angioten...

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Main Authors: Gul, Rukhsana, Ramdas, Maya, Mandavia, Chirag H., Sowers, James R., Pulakat, Lakshmi
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551408/
https://ncbi.nlm.nih.gov/pubmed/23381810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000343456
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