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Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice

The formation of the anteroposterior axis in mammals requires a Wnt3-dependent symmetry-breaking event that leads to the formation of the primitive streak and gastrulation. Wnt3 is expressed sequentially in two distinct areas of the mouse embryo before the appearance of the primitive streak; first i...

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Detalhes bibliográficos
Main Authors: Tortelote, Giovane G., Hernández-Hernández, J. Manuel, Quaresma, Alexandre J. C., Nickerson, Jeffrey A., Imbalzano, Anthony N., Rivera-Pérez, Jaime A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551248/
https://ncbi.nlm.nih.gov/pubmed/23085236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.10.013
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