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Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice

The formation of the anteroposterior axis in mammals requires a Wnt3-dependent symmetry-breaking event that leads to the formation of the primitive streak and gastrulation. Wnt3 is expressed sequentially in two distinct areas of the mouse embryo before the appearance of the primitive streak; first i...

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Autors principals: Tortelote, Giovane G., Hernández-Hernández, J. Manuel, Quaresma, Alexandre J. C., Nickerson, Jeffrey A., Imbalzano, Anthony N., Rivera-Pérez, Jaime A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551248/
https://ncbi.nlm.nih.gov/pubmed/23085236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.10.013
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