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Prolonged Toxicity after Amitriptyline Overdose in a Patient Deficient in CYP2D6 Activity
INTRODUCTION: Amitriptyline and its metabolite, nortriptyline, are metabolized, in part, by CYP2D6, a polymorphic enzyme. About 8% of Caucasians are deficient in CYP2D6 activity. CASE REPORT: We present the case of a comatose woman who intentionally overdosed on amitriptyline and displayed rising se...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer-Verlag
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3550197/ https://ncbi.nlm.nih.gov/pubmed/21614669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13181-011-0158-2 |
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