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The CYP2D6 polymorphism in relation to the metabolism of amitriptyline and nortriptyline in the Faroese population

AIM: To determine the frequency of CYP2D6 poor metabolizers (PMs) in a Faroese patient group medicated with amitriptyline (AT) and to investigate plasma concentrations of AT and metabolites in relation to CYP2D6. METHODS: CYP2D6 phenotype and genotype were determined in 23 Faroese patients treated w...

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Detalhes bibliográficos
Main Authors: Halling, Jónrit, Weihe, Pál, Brosen, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291274/
https://ncbi.nlm.nih.gov/pubmed/17764479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02969.x
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