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Enzymatic basis for the selective inhibition of varicella-zoster virus by 5-halogenated analogues of deoxycytidine.

5-Bromodeoxycytidine (BrdC) and 5-iododeoxycytidine, at a concentration of 100 mug/ml, effectively inhibit the replication of varicella-zoster (VZ) virus in tissue culture. No toxicity could be demonstrated in uninfected cells under the same conditions. Studies on the enzymatic basis for this select...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Dobersen, M J, Jerkofsky, M, Greer, S
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1976
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC355015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/185427/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.20.2.478-486.1976
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