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Enzymatic basis for the selective inhibition of varicella-zoster virus by 5-halogenated analogues of deoxycytidine.

5-Bromodeoxycytidine (BrdC) and 5-iododeoxycytidine, at a concentration of 100 mug/ml, effectively inhibit the replication of varicella-zoster (VZ) virus in tissue culture. No toxicity could be demonstrated in uninfected cells under the same conditions. Studies on the enzymatic basis for this select...

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Autors principals: Dobersen, M J, Jerkofsky, M, Greer, S
Format: Artigo
Idioma:Inglês
Publicat: 1976
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC355015/
https://ncbi.nlm.nih.gov/pubmed/185427
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