The effect of amifostine, a cytoprotective agent, on paraquat toxicity in mice

BACKGROUND: Paraquat (PQ) is a highly poisonous herbicide with a variety of toxic effects, most notably pulmonary fibrosis. In alveolar epithelial cells, it is converted to a PQ radical and subsequently generates other reactive species resulting in lipid peroxidation and cell destruction. Amifostine...

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Hlavní autoři: Wills, Brandon K., Aks, Steven E., Maloney, Gerry E., Rhee, James W., Brand, Rhonda, Sekosan, Marin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2007
Témata:
Toxicology Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3550126/
https://ncbi.nlm.nih.gov/pubmed/18072151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/BF03161031
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