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Mechanistic Evaluation of a Novel Small Molecule Targeting Mitochondria in Pancreatic Cancer Cells

BACKGROUND: Pancreatic cancer is one of the deadliest cancers with a 5-year survival rate of 6%. Therapeutic options are very limited and there is an unmet medical need for safe and efficacious treatments. Cancer cell metabolism and mitochondria provide unexplored targets for this disease. We recent...

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Detalhes bibliográficos
Main Authors: Shabaik, Yumna H., Millard, Melissa, Neamati, Nouri
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549929/
https://ncbi.nlm.nih.gov/pubmed/23349858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054346
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